GRUPO DE INVESTIGACIÓN
E006-01 BIOMEMBRANAS
Departamento  BIOQUÍMICA Y BIOLOGÍA MOLECULAR A
Centro  FACULTAD DE VETERINARIA
Dirección Campus Universitario de Espinardo
CP 30100
Teléfono 868884776
URLs de interés

Claves

  • ANTICANCERIGENOS
  • APOPTOSIS CELULAR
  • BIOMEMBRANAS
  • CANCER
  • DIACILGLICEROL
  • INTERACCION LIPIDO-PROTEINA
  • LIPOSOMAS
  • PROTEINA QUINASA C
  • PROTEINAS DE MEMBRANA
  • SEÑALIZACION CELULAR

Líneas de investigación

  • ESTRUCTURA Y FUNCION DE PROTEINA ANTIAPOPTOTICA BCL-2
    • Áreas UNESCO asociadas
      • Química >> Bioquímica >> BIOLOGIA MOLECULAR
      • Química >> Bioquímica >> BIOQUIMICA FISICA
    • Áreas tecnológicas asociadas
      • BIOLOGIA, MEDICINA >> BIOQUIMICA
      • BIOLOGIA, MEDICINA >> BIOINGENIERIA
      • BIOLOGIA, MEDICINA >> BIOFISICA
  • PROTEINA QUINASA C. ESTRUCTURA Y MODULACION DE SU ACTIVIDAD
    • Áreas UNESCO asociadas
      • Química >> Bioquímica >> LIPIDOS
      • Química >> Bioquímica >> BIOLOGIA MOLECULAR
      • Química >> Bioquímica >> BIOQUIMICA FISICA
      • Química >> Bioquímica >> PROTEINAS
    • Áreas tecnológicas asociadas
      • BIOLOGIA, MEDICINA >> BIOQUIMICA
      • BIOLOGIA, MEDICINA >> BIOINGENIERIA
      • BIOLOGIA, MEDICINA >> BIOFISICA

Tecnologías y servicios que oferta

  • ANTICANCERIGENOS
  • APOPTOSIS CELULAR
  • LIPOSOMAS. APLICACIONES
  • PROTEINA QUINASA C. MODULACION DE SU ACTIVIDAD

Técnicas y equipos de especial relevancia

  • CALORIMETRIA DIFERENCIAL DE BARRIDO
  • CLONACION DE ACIDOS NUCLEICOS
  • EXPRESION DE PROTEINAS RECOMBINANTES
  • FT-IR; FTIR-ATR
  • HPLC
  • PCR
  • PREPARACION DE LIPOSOMAS

Producción científica

Artículos
  • CORBALAN GARCIA, M. S., AUSILI A., TORRECILLAS SANCHEZ A., GOMEZ MURCIA V., GODOS DE FRANCISCO A.M.D., GOMEZ FERNANDEZ, J. C. ANTICANCER AGENT EDELFOSINE EXHIBITS A HIGH AFFINITY FOR CHOLESTEROL AND DISORGANIZES LIQUID-ORDERED MEMBRANE STRUCTURES.. LANGMUIR, VOL. 34, 8333--8346, (2018)
  • GOMEZ MURCIA V., TORRECILLAS SANCHEZ A., GOMEZ FERNANDEZ, J. C. INSIGHTS INTO THE IMPACT OF A MEMBRANE-ANCHORING MOIETY ON THE BIOLOGICAL ACTIVITIES OF BIVALENT COMPOUNDS AS POTENTIAL NEUROPROTECTANTS FOR ALZHEIMER'S DISEASE.. JOURNAL OF MEDICINAL CHEMISTRY, VOL. 61, 777--790, (2018)
  • GOMEZ FERNANDEZ, J. C. NANODESIGN OF NEW SELF-ASSEMBLING CORE-SHELL GELLAN-TRANSFERSOMES LOADING BAICALIN AND IN VIVO EVALUATION OF REPAIR RESPONSE IN SKIN.. NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY AND MEDICINE, VOL. 14, 569--579, (2018)
  • AUSILI A., TORRECILLAS SANCHEZ A., GODOS DE FRANCISCO A.M.D., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. PHENOLIC GROUP OF ¿-TOCOPHEROL ANCHORS AT THE LIPID-WATER INTERFACE OF FULLY SATURATED MEMBRANES.. LANGMUIR, VOL. 34, 3336--3348, (2018)
  • AUSILI A. WATERSPY: A HIGH SENSITIVITY, PORTABLE PHOTONIC DEVICE FOR PERVASIVE WATER QUALITY ANALYSIS.. SENSORS, VOL. 19, 33--, (2018)
  • GOMEZ FERNANDEZ, J. C. DEVELOPMENT OF POLY(LACTIDE-CO-GLICOLIDE) NANOPARTICLES INCORPORATING MORPHINE HYDROCHLORIDE TO PROLONG ITS CIRCULATION IN BLOOD.. CURRENT PHARMACEUTICAL DESIGN, VOL. 23, 2015--2025, (2017)
  • ACUÑA MELENDEZ O.S., AVILES SANCHEZ M., LOPEZ UBEDA R., GUILLEN MARTINEZ A.P., TORRECILLAS SANCHEZ A., COY FUSTER P., IZQUIERDO RICO M.J. DIFFERENTIAL GENE EXPRESSION IN PORCINE OVIDUCT DURING THE OESTROUS CYCLE.. REPRODUCTION FERTILITY AND DEVELOPMENT, VOL. 29, 2387--2399, (2017)
  • GOMEZ FERNANDEZ, J. C., ARANDA MARTINEZ F.J. NANODESIGN OF NEW SELF-ASSEMBLING CORE-SHELL GELLAN-TRANSFERSOMES LOADING BAICALIN AND IN VIVO EVALUATION OF REPAIR RESPONSE IN SKIN.. NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY AND MEDICINE, VOL. 14, 569--579, (2017)
  • PEREZ SANCHEZ M.D., CORONADO PARRA M.T., LOPEZ MARTINEZ D., BALTANAS COPADO J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S. STRUCTURAL CHARACTERIZATION OF THE RABPHILIN-3A-SNAP25 INTERACTION. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, VOL. 114, 5343--5351, (2017)
  • BALTANAS COPADO J., CORBALAN GARCIA, M. S. STRUCTURAL CHARACTERIZATION OF THE RABPHILIN-3A-SNAP25 INTERACTION.. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA, VOL. 114, 5343--5352, (2017)
  • AUSILI A., TORRECILLAS SANCHEZ A., ARANDA MARTINEZ F.J., GOMEZ FERNANDEZ, J. C. THE INCREASE IN POSITIVELY CHARGED RESIDUES IN CECROPIN D-LIKE GALLERIA MELLONELLA FAVORS ITS INTERACTION WITH MEMBRANE MODELS THAT IMITATE BACTERIAL MEMBRANES.. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, VOL. 629, 54--62, (2017)
  • AUSILI A., DE GODOS A., TORRECILLAS SANCHEZ A., ARANDA MARTINEZ F.J., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. THE VERTICAL LOCATION OF ¿-TOCOPHEROL IN PHOSPHATIDYLCHOLINE MEMBRANES IS NOT ALTERED AS A FUNCTION OF THE DEGREE OF UNSATURATION OF THE FATTY ACYL CHAINS.. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, VOL. 19, 6731--6742, (2017)
  • GOMEZ MURCIA V., TORRECILLAS SANCHEZ A., DE GODOS A., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. BOTH IDEBENONE AND IDEBENOL ARE LOCALIZED NEAR THE LIPID-WATER INTERFACE OF THE MEMBRANE AND INCREASE ITS FLUIDITY.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, VOL. 1858, 1071--1081, (2016)
  • GOMEZ MURCIA V., TORRECILLAS SANCHEZ A., DE GODOS A., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. X-RAY DIFFRACTION AND NMR DATA FOR THE STUDY OF THE LOCATION OF IDEBENONE AND IDEBENOL IN MODEL MEMBRANES.. DATA IN BRIEF, VOL. 7, 981--989, (2016)
  • AUSILI A., GOMEZ FERNANDEZ, J. C. ATTENUATED TOTAL REFLECTANCE INFRARED SPECTROSCOPY: A POWERFUL METHOD FOR THE SIMULTANEOUS STUDY OF STRUCTURE AND SPATIAL ORIENTATION OF LIPIDS AND MEMBRANE PROTEINS. BIOMEDICAL SPECTROSCOPY AND IMAGING, VOL. 4, 159--170, (2015)
  • TORRECILLAS A., FERNÁNDEZ MARTÍNEZ A.M.., AUSILI A., DE GODOS A., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. CAPSAICIN FLUIDIFIES THE MEMBRANE AND LOCALIZES ITSELF NEAR THE LIPID-WATER INTERFACE. ACS CHEMICAL NEUROSCIENCE, VOL. 6, 1741--1750, (2015)
  • MARIN VICENTE C. FUNCTIONAL IDENTIFICATION OF TARGET BY EXPRESSION PROTEOMICS (FITEXP) REVEALS PROTEIN TARGETS AND HIGHLIGHTS MECHANISMS OF ACTION OF SMALL MOLECULE DRUGS.. SCIENTIFIC REPORTS, VOL. 5, 11176--11176, (2015)
  • MARIN VICENTE C. RRP6/EXOSC10 IS REQUIRED FOR THE REPAIR OF DNA DOUBLE-STRAND BREAKS BY HOMOLOGOUS RECOMBINATION.. JOURNAL OF CELL SCIENCE, VOL. 128, 1097--1107, (2015)
  • GARCÍA MARTINEZ V. SPHINGOMYELIN DERIVATIVES INCREASE THE FREQUENCY OF MICROVESICLE AND GRANULE FUSION IN CHROMAFFIN CELLS. NEUROSCIENCE, VOL. 295, 117--125, (2015)
  • CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. CLASSICAL PROTEIN KINASES C ARE REGULATED BY CONCERTED INTERACTION WITH LIPIDS: THE IMPORTANCE OF PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE. BIOPHYSICAL REVIEWS, VOL. 6, 3--14, (2014)
  • GOMEZ FERNANDEZ, J. C., TORRECILLAS SANCHEZ A. CORRELATION BETWEEN FLUORESCENCE AND STRUCTURE IN THE ORANGE-EMITTING GFP-LIKE PROTEIN, MONOMERIC KUSABIRA ORANGE.. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, VOL. 138, 223--229, (2014)
  • CORONADO PARRA M.T. EFFECTS OF TWO LOW-SHRINKAGE COMPOSITES ON DENTAL STEM CELLS (VIABILITY, CELL DAMAGED OR APOPTOSIS AND MESENCHYMAL MARKERS EXPRESSION). JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, VOL. 24, 979--998, (2014)
  • GOMEZ FERNANDEZ, J. C. FUNCTIONS OF THE C-TERMINAL DOMAINS OF APOPTOSIS-RELATED PROTEINS OF THE BCL-2 FAMILY.. CHEMISTRY AND PHYSICS OF LIPIDS, VOL. 183, 77--90, (2014)
  • TORRECILLAS SANCHEZ A., GOMEZ FERNANDEZ, J. C. LAMELLAR GEL (Lβ) PHASES OF TERNARY LIPID COMPOSITION CONTAINING CERAMIDE AND CHOLESTEROL.. BIOPHYSICAL JOURNAL, VOL. 106, 621--630, (2014)
  • TORRECILLAS SANCHEZ A., GOMEZ FERNANDEZ, J. C. MEMBRANE PERMEABILIZATION INDUCED BY SPHINGOSINE: EFFECT OF NEGATIVELY CHARGED LIPIDS.. BIOPHYSICAL JOURNAL, VOL. 106, 2577--2584, (2014)
  • EGEA JIMENEZ A.L., FERNÁNDEZ MARTÍNEZ A.M.., PEREZ LARA F.A., GODOS DE FRANCISCO A.M.D., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE ENHANCES ANIONIC LIPID DEMIXING BY THE C2 DOMAIN OF PKCα.. PLOS ONE, VOL. 9, 1--10, (2014)
  • CORONADO PARRA M.T., CORBALAN GARCIA, M. S. SEÑALIZACIÓN CELULAR: PKC Y CÁNCER. EUBACTERIA, VOL. 32, 1--7, (2014)
  • CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. SIGNALING THROUGH C2 DOMAINS: MORE THAN ONE LIPID TARGET.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, VOL. 1838, 1536--1547, (2014)
  • EGEA JIMENEZ A.L., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C. THE C1B DOMAINS OF NOVEL PKCε AND PKCη HAVE A HIGHER MEMBRANE BINDING AFFINITY THAN THOSE OF THE ALSO NOVEL PKCδ AND PKCθ.. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, VOL. 1838, 1898--1909, (2014)
  • GARCÍA MARTINEZ V. THE POSITION OF MITOCHONDRIA AND ER IN RELATION TO THAT OF THE SECRETORY SITES IN CHROMAFFIN CELLS.. JOURNAL OF CELL SCIENCE, VOL. 127, 5105--5114, (2014)
Comités editoriales
  • CHEMISTRY AND PHYSICS OF LIPIDS. ISSN: 0009-3084
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • CHEMISTRY AND PHYSICS OF LIPIDS. ISSN: 0009-3084
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • CHEMISTRY AND PHYSICS OF LIPIDS. ISSN: 0009-3084
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • THESCIENTIFICWORLDJOURNAL. ISSN: 1537-744X
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
         PEDRO LOZANO RODRIGUEZ
  • TheScientificWorldJOURNAL. ISSN: 1537-744X
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
         FAUSTINO MARIN SAN LEANDRO
         JOSE SEBASTIAN CARRION GARCIA
         MARIA PILAR COY FUSTER
         ALFONSO BAÑOS TORRICO
         JESUALDO TOMAS FERNANDEZ BREIS
         RAFAEL VALENCIA GARCIA
         MARIA DOLORES MURCIA ALMAGRO
         PEDRO LOZANO RODRIGUEZ
         CARMEN MATAS PARRA
         EMILIO ARSENIO MARTINEZ GARCIA
  • Biomedical Spectroscopy and Imaging. ISSN: 2212-8794
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • Biomedical Spectroscopy and Imaging. ISSN: 2212-8794
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • Biophysical Reviews. ISSN: 0175-7571
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • Biophysical Reviews. ISSN: 1867-2469
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
  • Biophysical Reviews. ISSN: 1867-2450
    MIEMBRO/S
         JUAN CARMELO GOMEZ FERNANDEZ
Congresos
  • BALTANAS COPADO J., PEREZ SANCHEZ M.D., LOPEZ MARTINEZ D., GOMEZ FERNANDEZ, J. C.
    IV JORNADAS DOCTORALES DE LA UNIVERSIDAD DE MURCIA, MURCIA, 2018.
    MECHANISM OF THE PHOSPHOINOSITIDES BINDING SITE IN THE C2 DOMAIN
  • REVERTE RODENAS S., SERRANO LOPEZ E.M., CORONADO PARRA M.T., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    41 CONGRESO DE LA SEBBM, SAMTANDER, 2018.
    FATTY ACIDS REGULATE PKCA IN BREAST CANCER CELLS
  • GOMEZ FERNANDEZ, J. C., EGEA JIMENEZ A.L., CORBALAN GARCIA, M. S.
    6TH INTERNATIONAL IBERIAN BIOPHYSICS CONGRESSX IBEROAMERICAN CONGRESS OF BIOPHYSICS, CASTELLÓN DE LA PLANA, 2018.
    HOW IS THE INTERACTION OF THE C1B DOMAIN OF PKC" WITHMEMBRANE PHOSPHOLIPIDS?
  • CORBALAN GARCIA, M. S., CORONADO PARRA M.T., LOPEZ MARTINEZ D., PEREZ SANCHEZ M.D., BALTANAS COPADO J., GOMEZ FERNANDEZ, J. C.
    6TH INTERNATIONAL IBERIAN BIOPHYSICS CONGRESSX IBEROAMERICAN CONGRESS OF BIOPHYSICS, CASTELLÓN DE LA PLANA, 2018.
    C2 DOMAIN-CONTAINING PROTEINS AT THE PRE-SYNAPTIC SPACE:RABPHILIN 3A AS A PARADIGM
  • PEREZ SANCHEZ M.D., BALTANAS COPADO J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    FEBS3, JOINT CONGRESS OF THE BIOCHEMICAL SOCIETIES OF SPAIN, FRANCE AND PORTUGAL, BARCELONA, 2017.
    RABPHILIN 3A AS A PARADIGMOF PIP2/CA2+-DEPENDENT MEMBRANE INTERACTION
  • PEREZ SANCHEZ M.D., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    FEBS3: JOINT MEETING OF BIOCHEMICAL SCOIETIES OF SPAIN, FRANCE AND PORTUGAL, BARCELONA, 2017.
    CHARACTERIZATION OF THE PHOSPHOINOSITIDE BINDINGSITE IN C2 DOMAINS
  • CORONADO PARRA M.T., MARIN VICENTE C., REVERTE RODENAS S., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    FEBS3, JOINT MEETING OF THE BIOCHEMICAL SOCIETIES FROM SPAIN, FRANCE AND PORTUGAL, BARCELONA, 2017.
    CHARACTERIZATION OF THE DOWNREGULATIONOF PKCALPHA IN MCF7 CELLS
  • CORONADO PARRA M.T., LOPEZ MARTINEZ D., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    FEBS3, JOINT MEETING OF THE BIOCHEMICAL SOCIETIES OF SPAIN, FRANCE AND PORTUGAL, BARCELONA, 2017.
    INTERACTION OF RABPHILIN3A AND SNAP25IN LIVING CELLS
  • PEREZ SANCHEZ M.D., BALTANAS COPADO J., CORONADO PARRA M.T., LOPEZ MARTINEZ D., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    16TH CONGRESS OF THE SPANISH BIOPHYSICAL SOCIETY, SEVILLA, 2017.
    CHARACTERIZATION OF THE DUAL-MEMBRANE SPECIFITY OF RABPHILIN 3A
  • GOMEZ FERNANDEZ, J. C., TORRECILLAS SANCHEZ A., DE GODOS A., CORBALAN GARCIA, M. S.
    16TH CONGRESS OF THE SPANISH BIOPHYSICS SOCIETY, SEVILLA, 2017.
    INTERACTION OF DIETHYLSTILBESTROL WITH MODEL MEMBRANES AND ITSLOCATION IN THE MEMBRANE BILAYER
  • CORONADO PARRA M.T., LOPEZ MARTINEZ D., PEREZ SANCHEZ M.D., BALTANAS COPADO J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    16TH CONGRESS OF THE SPANISH BIOPHYSICS SOCIETY, SEVILLA, 2017.
    CHARACTERIZATION OF THE RABPHILIN3A AND SNAP25 INTERACTION IN PC12CELLS
  • GOMEZ FERNANDEZ, J. C., EGEA JIMENEZ A.L., CORBALAN GARCIA, M. S.
    19TH IUPAB CONGRESS AND 11TH EBSA CONGRESS, EDINBURGH, 2017.
    SOME POSITIVELY CHARGED AMINOACIDS ARE ESSENTIAL FOR THE BINDING OF C1B DOMAIN OF PKCE TO MEMBRANES
  • GOMEZ FERNANDEZ, J. C.
    IIILAFEBS, IX IBEROAMERICAN CONGRESS OF BIOPHYSICS,, TUCUMÁN, ARGENTINA, 2016.
    PROTEIN KINASES C ARE REGULATED BY CONCERTED INTERACTION WITH LIPIDS
  • GOMEZ MURCIA V., GOMEZ FERNANDEZ, J. C., ALMELA ROJO M.D.P.
    XI SPANISH-PORTUGUESE CONFERENCE ON CONTROLLED DRUG DELIVERY. REVOLUTIONARY APPROACHES IN NNOMEDICINE DEVELOPMENT., GRANADA, 2016.
    OPTIMIZATION AND STABILITY STUDY OF THE PREPARATION OF POLYLACTIDE-CO-GLYCOLIDE NANOPARTICLES INCORPORATING MORPHINE HYDROCHLORIDE TO PROLONG ITS BLOOD CIRCULATION
  • LOPEZ MARTINEZ D., CORONADO PARRA M.T., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    XXXIX CONGRESO DE LA SEBBM, SALAMANCA, 2016.
    MULTIFUNCIONAL C2 DOMAINS
  • BALTANAS COPADO J., PEREZ SANCHEZ M.D., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    XXXIX CONGRESO DE LA SEBBM, SALAMANCA, 2016.
    CHARACTERIZATION OF THE CALCIUM BINDING MODEOF RABPHILIN-3A
  • MARIN VICENTE C., REVERTE RODENAS S., GOMEZ FERNANDEZ, J. C.
    XXXIX CONGRESO DE LA SEBBM, SALAMANCA, 2016.
    ROLE OF PKC ALPHA IN BREAST CANCER PROGRESSION
  • GOMEZ FERNANDEZ, J. C., EGEA JIMENEZ A.L., CORBALAN GARCIA, M. S.
    XXXIX CONGRESO DE LA SEBBM, SALAMANCA, 2016.
    MECHANISM OF BINDING OF C1B DOMAIN OF PKC¿ TOLIPID MEMBRANES
  • ACUÑA MELENDEZ O.S., TORRECILLAS SANCHEZ A., JIMENEZ MOVILLA, M., BAUERSACHS S., AVILES SANCHEZ M.
    20TH ANNUAL CONFERENCE OF THE EUROPEAN SOCIETY FOR DOMESTIC ANIMAL REPRODUCTION (ESDAR) AND THE 13TH CONFERENCE OF THE SPANISH ASSOCIATION FOR ANIMAL REPRODUCTION (AERA), LISBOA, PORTUGAL, 2016.
    A COMPARATIVE ANALYSIS OF THE PROTEIN COMPOSITION OF THE OVIDUCTAL FUID AND BLOOD SERUM BY TWO DIMENSIONAL GEL ELECTROPHORESIS
  • ACUÑA MELENDEZ O.S., BAUERSACHS S., TORRECILLAS SANCHEZ A., JIMENEZ MOVILLA, M., AVILES SANCHEZ M.
    32ND MEETING OF THE EUROPEAN TRANSFER ASSOCIATION (AETE), BARCELONA, 2016.
    A COMPARATIVE ANALYSIS OF THE PROTEIN COMPOSITION OF THE OVIDUCTAL AND UTERINE FLUIDS IN CATTLE DURING THE PERIOVULATORY PHASE BY 2D FLUORESCENCE DIFFERENCE GEL ELECTROPHORESIS (DIGE)
  • GOMEZ FERNANDEZ, J. C.
    32O CONGRESO LATINOAMERICANO DE QUÍMICA, 2016.
    CALORIMETRIC AND SPECTROSCOPIC STUDIES OF THE CHARGE INFLUENCE ON INTERACTIONS BETWEEN PEPTIDES AND DMPC/DMPG BINARY MIXTURES
  • PEREZ SANCHEZ M.D., CORONADO PARRA M.T., BALTANAS COPADO J., LOPEZ MARTINEZ D., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    5TH IBERIAN BIOPHYSICS CONGRESS, OPORTO, PORTUGAL, 2016.
    CHARACTERIZATION OF THE CALCIUM BINDING MODE OF RABPHILIN 3A
  • GOMEZ FERNANDEZ, J. C., DE GODOS A., TORRECILLAS A., CORBALAN GARCIA, M. S.
    BIOPHYSICS OF PROTEINS AT SURFACES. ASSEMBLY, ACTIVATION, SIGNALING, MADRID, 2015.
    EDELFOSINE SHOWS AFFINITY FOR CHOLESTEROL AND DISORGANIZES LIQUID ORDERED STRUCTURES
  • GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    BIOPHYSICS OF PROTEINS AT SURFACES. ASSEMBLY, ACTIVATION, SIGNALING, MADRID, 2015.
    MEMBRANE SURFACE ACTIVATION OF PROTEIN KINASES C
  • CORONADO PARRA M.T., GUILLEN CASAS J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    FEBS-EMBO CONGRESS, 2015.
    STRUCTURAL INSIGHTS INTO THE CA2+ AND PI(4,5)P3 BINDING MODES OF THE C2 DOMAIN OF RABPHILIN 3A AND SYNAPTOTAGMIN 1
  • GOMEZ FERNANDEZ, J. C.
    FIP WORLD CONGRESS OF PHARMACY AND PHARMACEUTICAL SCIENCES 2015, 2015.
    OPTIMIZATION OF PLGA MORPHINE LOADED NANOPARTICLES
  • CORONADO PARRA M.T., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    I JORNADAS DOCTORALES DE LA UNIVERSIDAD DE MURCIA, 2015.
    PKC, A KEY SWITCH IN CANCER SIGNALING PATHWAYS
  • GOMEZ FERNANDEZ, J. C.
    I JORNADAS DOCTORALES UNIVERSIDAD DE MURCIA, 2015.
    CARACTERIZACIÓN Y ESTUDIOS DE LIBERACIÓN IN VITRO DE MORFINA A TRAVÉS DE FORMULACIONES DE NANOPARTÍCULAS Y LIPOSOMAS
  • GOMEZ FERNANDEZ, J. C.
    INTERNATIONAL ARGENTINA-URUGUAY BIOPHYSICS MEETING, SALTO (URUGUAY), 2015.
    LIPID ACTIVATION OF PROTEIN KINASES C
  • GOMEZ FERNANDEZ, J. C.
    INTERNATIONAL OPIOIDS CONFERENCE (ICOO 2015), 2015.
    FORMULATION AND PHARMACOKINETICS OF PEGYLATED LIPOSOMAL MORPHINE
  • GOMEZ FERNANDEZ, J. C.
    POSLATAM 2015, SALTO (URUGUAY), 2015.
    CURRENT MODELS OF MEMBRANE STRUCTURE AND PROTEIN-LIPID INTERACTIONS
  • GOMEZ FERNANDEZ, J. C.
    XII CONGRESO DE SOCIEDAD ESPAÑOLA DE FARMACIA INDUSTRIAL Y GALÉNICA, 2015.
    COMPARACIÓN DE DIFERENTES FORMULACIONES DE NANOPARTÍCULAS PARA LA ENCAPSULACIÓN DE MORFINA
  • GODOS DE FRANCISCO A.M.D., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C.
    XVTH CONGRESS OF THE SPANISH BIOPHHYSICAL SOCIETY, GRANADA, 2015.
    LOCALIZATION OF IDEBENONE AND IDEBENOL IN MEMBRANES BY USING SOLID-STATE-NMR
  • CORBALAN GARCIA, M. S., CORONADO PARRA M.T., REVERTE RODENAS S., MARIN VICENTE C., GOMEZ FERNANDEZ, J. C.
    XXXVIII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA CELULAR, VALENCIA, 2015.
    DOWN-MODULATION OF PKC INDUCES A DIFFERENTIAL GENE EXPRESSION PROFILE IN BREAST CANCER CELLS
  • GOMEZ FERNANDEZ, J. C.
    XXXVIII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR, 2015.
    DOWN-MODULATION OF PKCA INDUCEA A DIFFERENTIAL GENE EXPRESSION PROFILE IN BREAST CANCER CELLS
  • GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    XXXVIII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR, 2015.
    CHARACTERIZATION OF THE LIPID-BINDING PROPERTIES OF C2 DOMAINS INVOLVED IN VESICULAR TRAFFIC
  • CORONADO PARRA M.T., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    XXXVIII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR, VALENCIA, 2015.
    EFFECT OF SALINOMYCIN TREATMENT ON THE MALIGNANT PROPERTIES OF BREAST CANCER CELLS
  • TORRECILLAS A., GODOS DE FRANCISCO A.M.D., CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C.
    10TH EUROPEAN BIOPHYSICS CONGRESS, DRESDE, 2015.
    INTERACTION OF IDEBENONE WITH MODEL MEMBRANES AND ITS LOCATION IN THE BILAYER
  • GOMEZ FERNANDEZ, J. C.
    36TH CONGRESS SPANISH PHARMACOLOGICAL SOCIETY, 2015.
    PROLONGED ANALGESIA WITH MULTILAMELAR AND PEGYLATED UNILAMELAR LIPOSOMAL MORPHINE IN MICE
  • GOMEZ FERNANDEZ, J. C.
    75TH FIP WORLD CONGRESS OF PHARMACY AND PHARMACEUTICAL SCIENCES 2015, 2015.
    A STUDY ON THE ENCAPSULATION OF MORPHINE INTO LIPOSOMAL CARRIERS AND PHARMACOKINETICS
  • PEREZ SANCHEZ M.D., CORONADO PARRA M.T., GUILLEN CASAS J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    FEBS-EMBO CONGRESS PARIS 2014, PARIS, 2014.
    STRUCTURAL INSIGHTS INTO THE CA2+ AND PI(4,5)P2 BINDING MODES OF THE C2 DOMAINS OF RABPHILIN 3A AND SYNAPTOTAGMIN I
  • GOMEZ FERNANDEZ, J. C.
    FESBE 2014, CAXAMBÚ, BRASIL, 2014.
    CURRENT MODELS OF MEMBRANE STRUCTURE AND PROTEIN-LIPID INTERACTION
  • GOMEZ FERNANDEZ, J. C.
    FESBE 2014, CAXAMBÚ, BRASIL, 2014.
    PROTEIN KINASE C: BERSATILE GTRANSDUCERS OF CELL SIGNALING
  • GOMEZ FERNANDEZ, J. C., AUSILI A., FERNÁNDEZ MARTÍNEZ A.M.., CORBALAN GARCIA, M. S.
    IUPAB INTERNATIONAL BIOPHYSICS CONGRESS, BRISBANE, AUSTRALIA, 2014.
    CAPSAICIN DISORDERS AND FLUIDIFIES DPPC MODEL MEMBRANES
  • GOMEZ FERNANDEZ, J. C., EGEA JIMENEZ A.L., FERNÁNDEZ MARTÍNEZ A.M.., PEREZ LARA F.A., GODOS DE FRANCISCO A.M.D., CORBALAN GARCIA, M. S.
    IUPAB INTERNATIONAL BIOPHYSICS CONGRESS 2014, BRISBANE, AUSTRALIA, 2014.
    MEMBRANE LIPID DEMIXING BY THE C2 DOMAIN OF PKCα
  • TORRECILLAS SANCHEZ A., GOMEZ FERNANDEZ, J. C.
    IUPAB INTERNATIONAL BIOPHYSICS CONGRESS 2014, BRISBANE, AUSTRALIA, 2014.
    MEMBRANE PERMEABILIZATION INDUCED BY SPHINGOSINE: EFFECT OF NEGATIVELY-CHARGED LIPIDS
  • PEREZ SANCHEZ M.D., CORONADO PARRA M.T., GUILLEN CASAS J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    XIV CONGRESS OF THE SPANISH BIOPHYSICAL SOCIETY (SBE 2014), ALCALÁ DE HENARES, 2014.
    CHARACTERIZATION OF THE C2 DOMAINS OF RABPHILIN 3A AND SYNAPTOTAGMIN 1
  • CORBALAN GARCIA, M. S., GOMEZ FERNANDEZ, J. C.
    XIV CONGRESS OF THE SPANISH BIOPHYSICAL SOCIETY (SBE 2014), ALCALÁ DE HENARES, 2014.
    C2 DOMAINS: MANY WAYS TO RECOGNIZE SPECIFIC LIPIDS AT THE MEMBRANE
  • GOMEZ FERNANDEZ, J. C., EGEA JIMENEZ A.L., CORBALAN GARCIA, M. S.
    XIV CONGRESS OF THE SPANISH BIOPHYSICAL SOCIETY (SBE 2014), ALCALÁ DE HENARES, 2014.
    C1B DOMAINS OF NOVEL PKCS SHOW DIFFERENT AFFINITIES TO BIND TO MODEL AND CELL MEMBRANES, AS A FUNCTION OF NEGATIVELY CHARGED PHOSPHOLIPIDS AND DIACYLGLYCEROLS
  • PEREZ SANCHEZ M.D., CORONADO PARRA M.T., GUILLEN CASAS J., GOMEZ FERNANDEZ, J. C., CORBALAN GARCIA, M. S.
    XXXVII CONGRESO DE LA SEBBM, GRANADA, 2014.
    STRUCTURAL INSIGHTS INTO THE CA+2 AND PI(4,5)P2 BINDING MODES OF THE C2 DOMAINS OF RABPHILIN 3A AND SYNAPTOTAGMIN 1
  • CORBALAN GARCIA, M. S., CORONADO PARRA M.T., PEREZ SANCHEZ M.D., GOMEZ FERNANDEZ, J. C.
    XXXVII CONGRESO DE LA SEBBM, GRANADA, 2014.
    MODULATION OF THE PLASMA MEMBRANE LOCALIZATION AND ACTIVATION OF PKCALPHA BY FATTY ACIDS TREATMENT
Comité organizador y/o científico de congresos
  • GOMEZ FERNANDEZ, J. C.
    6TH INTERNATIONAL IBERIAN BIOPHYSICS CONGRESSX IBEROAMERICAN CONGRESS OF BIOPHYSICS, 2018.
  • GOMEZ FERNANDEZ, J. C.
    16TH CONGRESS OF THE SPANISH BIOPHYCS SOCIETY, SEVILLA, 2017.
  • GOMEZ FERNANDEZ, J. C.
    IIILAFEBS, IX IBEROAMERICAN CONGRESS OF BIOPHYSICS, XLV SAB ANNUAL MEETING, TUCUMÁN, ARGENTINA, 2016.
  • GOMEZ FERNANDEZ, J. C.
    5TH IBERIAN BIOPHYSICS CONGRESS, OPORTO, PORTUGAL, 2016.
  • GOMEZ FERNANDEZ, J. C.
    XVTH CONGRESS OF THE SPANISH BIOPHYSICAL SOCIETY, GRANADA, 2015.
  • GOMEZ FERNANDEZ, J. C.
    XIV CONGRESS OF THE SPANISH BIOPHYSICAL SOCIETY, ALCALÁ DE HENARES, 2014.
Tesis
  • 007317  CHARACTERIZATION OF THE STRUCTURE AND FUNCTION OF THE RABPHILIN 3A / CARACTERIZACIÓN DE LA ESTRUCTURA Y FUNCIÓN DE LA RABFILINA 3A.
    DOCTOR: MARIA DOLORES PEREZ SANCHEZ
    FECHA DE LECTURA: 24/07/2017
    DIRECTOR/ES
         MARIA SENENA CORBALAN GARCIA
         JUAN CARMELO GOMEZ FERNANDEZ
  • 007302  DUAL-TARGETING IMPLICATION IN THE REGULATION OF PERIPHERAL MEMBRANE PROTEINS / FUNCIÓN DEL MECANISMO DE DOBLE DIANA EN LA REGULACIÓN DE PROTEÍNAS PERIFÉRICAS DE MEMBRANA.
    DOCTOR: MARIA TERESA CORONADO PARRA
    FECHA DE LECTURA: 24/07/2017
    DIRECTOR/ES
         MARIA SENENA CORBALAN GARCIA
         JUAN CARMELO GOMEZ FERNANDEZ
Tesis de Master y Diplomas de estudios avanzados
  • CARACTERIZACIÓN DEL MECANISMO UNIÓN DE VESÍCULAS LIPÍDICAS AL DOMINIO C2AB DE LA RABFILINA 3A
    TESINANDO: ÁLVARO HERNÁNDEZ SÁEZ
    TIPO: TESIS DE MASTER
    FECHA DE LECTURA: 03/07/2015
    DIRECTOR/ES
         MARIA SENENA CORBALAN GARCIA
  • TRANSMISIÓN DE SEÑALES A TRAVÉS DE MEMBRANAS
    TESINANDO: FRANCISCO MORENO GARCÍA
    TIPO: TESIS DE MASTER
    FECHA DE LECTURA: 10/09/2014
    DIRECTOR/ES
         MARIA SENENA CORBALAN GARCIA
  • TRANSMISIÓN DE SEÑALES A TRAVÉS DE MEMBRANAS
    TESINANDO: MARCOS GRAGERA CABEZUDO
    TIPO: TESIS DE MASTER
    FECHA DE LECTURA: 07/07/2014
    DIRECTOR/ES
         MARIA SENENA CORBALAN GARCIA
Trabajos de fin de Master
  • Edición mediante sistema CRISPR/Cas9 de PKC Alpha en línea celular MDA-MB-231
    AUTOR: CABRERA GOMEZ, CAROLINA GISEL
    FECHA DE LECTURA: 13/09/2018
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
  • Transmisión de señales a través de membranas
    AUTOR: SERRANO LOPEZ, EMILIO MANUEL
    FECHA DE LECTURA: 04/07/2017
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
  • Rabfilina3A favorece la localización de SNAP25A en células PC12
    AUTOR: LOPEZ MARTINEZ, DAVID
    FECHA DE LECTURA: 27/06/2016
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
  • Caracterización molecular de la interacción de proteínas que regulan la exocitosis neuronal: Rabfilina-3A
    AUTOR: BALTANAS COPADO, JESUS
    FECHA DE LECTURA: 27/06/2016
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
  • caracterizacion del mecanismo de union de vesículas lipídicas al dominio C2AB de la rabfilina 3A
    AUTOR: HERNANDEZ SAEZ, ALVARO
    FECHA DE LECTURA: 22/06/2015
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
  • CARACTERIZACIÓN DEL MECANISMO DE AGREGACIÓN DE VESÍCULAS LIPÍDICAS INDUCIDO POR EL DOMINO C2AB DE LA RABFILINA-3A.
    AUTOR: MORENO GARCIA, FRANCISCO
    FECHA DE LECTURA: 04/09/2014
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
  • ANÁLISIS DE EXPRESIÓN DE GENES REGULADOS POR LA PROTEÍNA QUINASA C ALFA EN CÉLULAS DE CÁNCER DE MAMA. VALIDACIÓN DE MICROARRAY DE cDNA MEDIANTE PCR CUANTITATIVA.
    AUTOR: GRAGERA CABEZUDO, MARCOS
    FECHA DE LECTURA: 30/06/2014
    DIRECTOR/ES: CORBALAN GARCIA, MARIA SENENA
Proyectos
  • BFU2011-22828
    ESTUDIOS BIOFÍSICOS Y CELULARES DE PROTEÍNAS QUINASAS C: ESTRUCTURA, MECANISMOS DE ACTIVACIÓN Y PAPEL REGULADOR EN LA CÉLULA
    ENTIDAD: MINISTERIO DE CIENCIA E INNOVACIÓN
    COMIENZO: 01/01/2012, FIN: 30/06/2015
    INVESTIGADORES PRINCIPALES
         JUAN CARMELO GOMEZ FERNANDEZ
  • BFU2014-52269-P
    INTERACIONES DE PROTEÍNAS MULTIDOMINIO CON MEMBRANAS: PROTEINAS QUINASAS C Y RABFILINA 3A COMO PARADIGMAS
    ENTIDAD: MINISTERIO DE ECONOMÍA Y COMPETITIVIDAD
    COMIENZO: 01/01/2015, FIN: 30/06/2018
    INVESTIGADORES PRINCIPALES
         MARIA SENENA CORBALAN GARCIA
  • 19409/PI/14
    INTERACCIONES DE LAS PKCS CON MEMBRANAS CELULARES:UN EJEMPLO DE POSIBLE APLICACIÓN TERAPÉUTICA
    ENTIDAD: FUNDACION SENECA
    COMIENZO: 01/07/2015, FIN: 31/12/2018
    INVESTIGADORES PRINCIPALES
         MARIA SENENA CORBALAN GARCIA
  • BFU2017-87222-P
    CARACTERIZACIÓN ESTRUCTURAL Y FUNCIONAL DE PROTEÍNAS PERIFÉRICAS DE MEMBRANA INVOLUCRADAS EN SEÑALIZACIÓN CELULAR Y FUSIÓN DE MEMBRANAS
    ENTIDAD: MINISTERIO DE ECONOMÍA, INDUSTRIA Y COMPETITIVIDAD
    COMIENZO: 01/01/2018, FIN: 31/12/2020
    INVESTIGADORES PRINCIPALES
         MARIA SENENA CORBALAN GARCIA
         JUAN CARMELO GOMEZ FERNANDEZ
Proyectos U.E.
  • INSTRUCT CALL FOR R&D PILOT
    STRUCTURAL BIOLOGY OF PKCÁ-PROTEIN COMPLEXES IN CANCER
    PROGRAMA: 
    PARTICIPACIÓN: LIDER
    COMIENZO: 01/02/2017, FIN: 31/12/2018
    INVESTIGADORES PRINCIPALES
         MARIA SENENA CORBALAN GARCIA
Contratos
  • LINEA DE I+D BASADA EN EL ESTUDIO DE APLICACIÓN DE LA BIOTECNOLOGÍA EN LA MEJORA MEDIOAMBIENTAL DE LOS PROCESOS DE TINTURA TEXTIL (LIPOENZYM)
    ENTIDAD: ASOCIACIÓN DE INVESTIGACIÓN DE LA INDUSTRIA TEXTIL (AITEX)
    COMIENZO: 25/09/2015, FIN: 25/03/2016
    INVESTIGADORES PRINCIPALES
         JUAN CARMELO GOMEZ FERNANDEZ
  • LÍNEA DE I+D BASADA EN EL ESTUDIO DE APLICACIÓN DE LA BIOTECNOLOGÍA EN LA MEJORA AMBIENTAL DE LOS PROCESOS DE TINTURA TEXTIL (LIPOENZYM II)
    ENTIDAD: ASOCIACIÓN DE INVESTIGACIÓN DE LA INDUSTRIA TEXTIL (AITEX)
    COMIENZO: 12/05/2016, FIN: 31/12/2016
    INVESTIGADORES PRINCIPALES
         JUAN CARMELO GOMEZ FERNANDEZ
  • CARACTERIZACIÓN DE MUESTRAS LÍPIDICAS
    ENTIDAD: BRILL PHARMA S.L
    COMIENZO: 11/12/2017, FIN: 10/01/2018
    INVESTIGADORES PRINCIPALES
         MARIA SENENA CORBALAN GARCIA
  • ESTABILIDAD VENENO HIMENÓPTEROS
    ENTIDAD: PROBELTE PHARMA, S.A.
    COMIENZO: 15/01/2018, FIN: 14/01/2021
    INVESTIGADORES PRINCIPALES
         JUAN CARMELO GOMEZ FERNANDEZ